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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP3
All Species:
8.79
Human Site:
S149
Identified Species:
16.11
UniProt:
P51452
Number Species:
12
Phosphosite Substitution
Charge Score:
0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51452
NP_004081.1
185
20478
S149
R
Q
K
M
D
V
K
S
A
L
S
I
V
R
Q
Chimpanzee
Pan troglodytes
P0C594
220
25358
D172
H
K
D
M
T
L
V
D
A
I
Q
Q
V
A
K
Rhesus Macaque
Macaca mulatta
XP_001113728
144
16144
D134
A
Q
L
C
Q
L
N
D
R
L
A
K
E
G
K
Dog
Lupus familis
XP_537624
228
25143
S192
R
Q
K
M
D
V
K
S
A
L
S
I
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7X3
185
20454
S149
R
Q
K
M
D
V
K
S
A
L
S
T
V
R
Q
Rat
Rattus norvegicus
P0C595
215
24055
D171
H
K
N
M
T
L
V
D
A
I
Q
Q
V
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506876
252
28589
D217
C
E
N
M
T
L
L
D
A
I
R
A
V
R
S
Chicken
Gallus gallus
P0C597
214
24304
D164
Y
K
N
M
T
V
V
D
A
I
E
Q
V
S
R
Frog
Xenopus laevis
Q4KL92
209
23732
E163
Y
K
N
M
T
V
V
E
S
I
T
Q
V
L
K
Zebra Danio
Brachydanio rerio
Q29RA3
189
21985
Q152
Q
Q
R
M
S
L
L
Q
A
V
E
Q
L
A
H
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
D164
E
H
S
L
S
V
V
D
A
I
E
H
V
R
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624869
211
24264
D176
K
K
E
M
L
A
T
D
A
I
R
T
V
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791989
192
21775
Q151
S
R
N
M
T
A
Q
Q
A
A
T
T
V
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.7
77.8
79.3
N.A.
92.9
39.5
N.A.
33.3
34.5
36.3
40.2
42.8
N.A.
40.7
N.A.
45.8
Protein Similarity:
100
55.4
77.8
79.8
N.A.
96.2
56.7
N.A.
47.2
51.4
54.5
57.1
57.6
N.A.
58.2
N.A.
64
P-Site Identity:
100
20
13.3
100
N.A.
93.3
20
N.A.
26.6
26.6
20
20
33.3
N.A.
26.6
N.A.
26.6
P-Site Similarity:
100
46.6
33.3
100
N.A.
93.3
46.6
N.A.
46.6
46.6
53.3
53.3
46.6
N.A.
60
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
0
85
8
8
8
0
24
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
24
0
0
54
0
0
0
0
0
0
0
% D
% Glu:
8
8
8
0
0
0
0
8
0
0
24
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
16
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
54
0
16
0
0
0
% I
% Lys:
8
39
24
0
0
0
24
0
0
0
0
8
0
0
39
% K
% Leu:
0
0
8
8
8
39
16
0
0
31
0
0
8
8
0
% L
% Met:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
39
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
39
0
0
8
0
8
16
0
0
16
39
0
0
31
% Q
% Arg:
24
8
8
0
0
0
0
0
8
0
16
0
0
54
8
% R
% Ser:
8
0
8
0
16
0
0
24
8
0
24
0
0
8
8
% S
% Thr:
0
0
0
0
47
0
8
0
0
0
16
24
0
0
0
% T
% Val:
0
0
0
0
0
47
39
0
0
8
0
0
85
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _